How stem cell therapy helps diabetic patients?
Diabetes is a
medical condition, in which the body is unable to properly regulate sugar in
the body. It is a lifelong condition, which can be controlled but a cure for
which is yet to be discovered. Diabetes has affected more than four hundred
million worldwide, and this number is rapidly increasing. Diabetes can cause a
number of life-threatening health
problems like strokes, cataracts, heart attacks, kidney failure, and nerve
damage to name a few. In some cases, it
can be controlled with a combination of insulin or other drugs, diet and
regular exercise.
In Type 1
diabetes, your body attacks itself and destroys the beta cells. It implies that
the body is unable to produce insulin, which makes is unable to deliver the
necessary glucose to the cells.
In Type 2
diabetes, in spite of body producing the insulin, the body remains unable to
glucose to the cells.
Stem cells
Stem cells
have the ability to transform into a type
of cell in the human body. Stem cells function to provide new cells in the body
and also replace cells that have been lost or damaged.
Stem cells
have no defined purpose. But can transform into specific cells as per the
body’s requirement. They are being researched to study how different functions
of the body work and how they sometimes go wrong.
Stem cells
are being investigated by scientists for
fighting diseases that currently have no cure.
They can be
manipulated into becoming targeted cells, which are then used to repair or
regenerate damaged cells.
Researches are
currently being done for diseases like Type 1 diabetes, stroke, burns, cancer,
spinal cord injuries, heart disease, Alzheimer’s, etc.
Stem cell therapy for diabetes
With such a
high ration of the world’s population under the grasp of this disease, there is
an increasing demand for finding a cure. Stem cell therapy is being used to study the way in which our bodies process
sugar.
The clinical
trials conducted with animals have proved to be immensely successful, which has
resulted in a number of human clinical trials. The mesenchymal stem cells are
being used in these trials for two purposes. Firstly, their usefulness is being
evaluated in directly treating diabetes.
Secondly, they are evaluated for treating complications caused by diabetes.
Stem cell therapy for diabetes has a bright future. Research is ongoing
where these cells are used as a way to create beta cells which can be
transplanted into the patients suffering from type 1 diabetes and also
protecting the beta cells from further damage.
The key for
this approach to work is to plant these beta cells in the part of the body
where they can defend the immune system’s attack. This can be achieved by
placing the beta cells in protective capsules. These capsules are designed to
allow insulin and glucose, as well as shielding the beta cells from the immune
system.
For type 1
diabetes, a number of clinical trials are already being conducted. But further
research is required to make sure whether any of these approaches is safe and effective.
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